DART-TOF for Analysis of Bulk Drugs [Agilent]Lisa Malette
The purpose of reviewable data is that any scientist could analyze the data and reach the same conclusion as the original scientist. The increased levels of quality led to concerns of decreases in case output from laboratory management thus leading to the need for a comprehensive screening instrument that would streamline the workflow. A Direct Analysis in Real Time (DART) ion source coupled to an Agilent time of flight (TOF) mass spectrometer (MS) provides an instrument capable of screening a multitude of sample types without any sample preparation necessary.
The Agilent DART-TOF MS has the added benefit of a continuous introduction of reference ions creating a built-in “positive control” that ensures proper instrument conditions across analyses. Using the Agilent DART-TOF MS, the analysis time per sample is 4 minutes including a blank resulting in a tremendous amount of reviewable data with minimal analysis time and sample preparation. At ADFS, a scientist averages 40 samples in a 4 hour period including data analysis. This initial screening procedure has been incorporated into the Drug Chemistry workflow for all incoming cases with the exception of marijuana and pharmaceutical tablets. The DART-TOF MS screen has streamlined the batching process for Drug Chemistry cases, allowing the laboratory to meet demanding quality standards without sacrificing efficiency.
Price: Funding for this course has been provided by Agilent Technologies
Course Type: On-Demand Presentation
Section: Forensic toxicology
Length: Approximately 30 minutes
Audience: Forensic Practitioners
Course Accreditation: Certificate of Attendance