Confirmatory Blood Identification by Mass-spectrometry Adapting Proteomics to Forensic Biology [Agilent]ftcoe_admin
While DNA profiling makes it possible to individualize biological stains, the accurate and unambiguous identification of the stain itself represents a significant challenge for forensic serologists. Current chemical, enzyme activity, and antibody-based assays used by forensic practitioners commonly offer only a presumptive indication of a target body fluid while consuming unacceptable quantities of precious evidence. Often times this leaves the forensic analyst without a reliable means of identifying those items of evidence that are more likely to yield probative results. In addition, for cases where only trace evidence is available, analysts may only obtain DNA results without the critical context that serological information can provide. Thus, there is clear value in developing more accurate, sensitive and robust approaches for identifying biological stains.
Through prior support for basic research from the National Institute of Justice, a total proteome biomarker discovery and validation initiative has already identified comprehensive panels of high-specificity protein biomarkers. Using these markers, a rapid UHPLC Q-TOF based workflow has been designed and successfully applied to actual case samples in collaboration with the Brasilia Civil Police.
For Forensic use.
Price: Funding for this course has been provided by Agilent Technologies
Course Type: On-Demand Presentation
Section: Forensic sciences, Forensic technology, Forensic toxicology
Length: Approximately 60 minutes
Audience: Forensic Practitioners
Course Accreditation: Certificate of Attendance